CAIS2 is the second generation of NIOD’s multi-awardwinning Copper Amino Isolate Serum. Copper Amino Isolate Serum 2:1 replaces Copper Amino Isolate Serum 1%.

As a highly-focused effort to maintain healthy-looking skin, this pro-repair, pro-collagen serum offers a novel approach to target all signs of skin aging indirectly. This indirect approach departs from the traditional thinking of addressing visible aspects of skin aging individually and instead forms a foundation to respect skin health.

While the first generation of CAIS 1% contained direct GHK copper peptides (known as GHK-Cu), this second generation Copper Amino Isolate Serum 2:1 contains 2% of pure GHK peptide of which 1% branches with copper ions upon mixing with NIOD’s patent-pending approach, forming 1% freshlyassembled, pro-repair GHK-Cu (copper peptides) and leaving 1% free-form, pro-collagen GHK peptide. This update also includes the addition of collagen-support peptides, Tripeptide-29, Acetyl Tetrapeptide-2 and Trifluoroacetyl Tripeptide-2. The base system of CAIS2 combines monodispersed, plant-derived glycogen, penetration-enhancing Myristoyl Nonapeptide-3 and cross-linked hyaluronic acid.

Finally, while CAIS required a neutral pH, CAIS2 is stable and effective in the pH range between 4.5 (acidic) and 7.4 (alkaline). CAIS2 does not require refrigeration.

Directions:Recommended as a core NIOD regimen product to be used twice daily, after cleansing, before the application of other skin treatments. NIOD recommends the application of Multi-Molecular Hyaluronic Complex (MMHC) after the application of this product.